Consumption

Yes. Whether your body carries the bacteria that naturally produces S-equol or not, there is no harm in taking an S-equol dietary supplement in accordance with label directions.

According to clinical studies, approximately one hour after ingestion of S-equol, the amount of S-equol in the blood reaches its peak level, and it subsides quickly afterward by passing out into the urine. After 48 hours, it becomes undetectable in urine. Therefore, it is concluded that S-equol remains in the body less than 48 hours. When an S-equol-producer consumes soy with daidzein, S-equol becomes detectable in the blood after 6 to 8 hours, and it reaches its peak after 12 hours. The timeline is slower because the soy isoflavone daidzein needs to be first processed by intestinal bacteria.

Although studies have not indicated any particular reason to suspect interference, you should consult with your physician or healthcare professional before taking S-equol if you are already taking medications or other supplements.

You should consult with your physician or healthcare professional before taking S-equol if you are already taking hormone replacement therapy.

S-equol has not been tested in women who have had breast cancer. Because S-equol has not been formally tested in women with breast cancer it is advised that you check with your physician or health care professional.

S-equol has not been tested in women who take synthetic thyroid medications. However, S-equol had negligible effect for thyroid hormones in the previous clinical studies. It is always advisable for women to consult their physicians or health care professionals regarding dietary supplements.